Inhibition of acetylcholinesterase and butyrylcholinesterase by a plant secondary metabolite boldine
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F18%3A39912328" target="_blank" >RIV/00216275:25310/18:39912328 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G44__/18:43889491
Result on the web
<a href="http://dx.doi.org/10.1155/2018/9634349" target="_blank" >http://dx.doi.org/10.1155/2018/9634349</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2018/9634349" target="_blank" >10.1155/2018/9634349</a>
Alternative languages
Result language
angličtina
Original language name
Inhibition of acetylcholinesterase and butyrylcholinesterase by a plant secondary metabolite boldine
Original language description
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are two enzymes sensitive to various chemical compounds having ability to bind to crucial parts of these enzymes. Boldine is a natural alkaloid and it was mentioned in some older works that it can inhibit some kinds ofAChE.We reinvestigated this effect onAChE and also on BChE using acetyl (butyryl) thiocholine and Ellman’s reagents as standard substances for spectrophotometric assay.We found out IC50 of AChE equal to 372
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomed Research International
ISSN
2314-6133
e-ISSN
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Volume of the periodical
Neuveden
Issue of the periodical within the volume
2018
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
"9634349-1"-"9634349-5"
UT code for WoS article
000429260400001
EID of the result in the Scopus database
2-s2.0-85045755692