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Catalytic oxidation of dopamine: mushroom tyrosinase vs. dinuclear copper(II) complex

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F21%3A39917554" target="_blank" >RIV/00216275:25310/21:39917554 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Catalytic oxidation of dopamine: mushroom tyrosinase vs. dinuclear copper(II) complex

  • Original language description

    The aim of this scientific study was to compare catecholase activity (representing the ability to oxidize ortho-diphenols) of tyrosinase enzyme (isolated from the common mushroom Agaricus bisporus) with a completely synthetic dinuclear copper complex toward the neurotransmitter dopamine using standard Michaelis-Menten kinetics model. Both, standard UV–Vis spectrophotometry and amperometry in a batch configuration were presented as complementary methods to study the catecholase activity. Despite the finding of comparable catalytic activity (similar Michaelis–Menten constants), it is necessary to mention that tyrosinase enzyme is not active in methanol solution like investigated dinuclear copper(II) complex.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Result continuities

  • Project

    <a href="/en/project/GA19-03160S" target="_blank" >GA19-03160S: Electrochemical study on new artificial enzymes and their role in sensing of neurotransmitters</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    XL. Moderní elektrochemické metody : sborník přednášek

  • ISBN

    978-80-905221-8-3

  • ISSN

  • e-ISSN

  • Number of pages

    4

  • Pages from-to

    221-224

  • Publisher name

    BEST Servis

  • Place of publication

    Ústí nad Labem

  • Event location

    Jetřichovice

  • Event date

    Nov 8, 2021

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article