Separation of Drugs by Commercial Nanofiltration Membranes and Their Modelling

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F22%3A39918776" target="_blank" >RIV/00216275:25310/22:39918776 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/2077-0375/12/5/528/htm" target="_blank" >https://www.mdpi.com/2077-0375/12/5/528/htm</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/membranes12050528" target="_blank" >10.3390/membranes12050528</a>

Result language

angličtina

Original language name

Separation of Drugs by Commercial Nanofiltration Membranes and Their Modelling

Original language description

Pharmaceutical drugs have recently emerged as one the foremost water pollutants in the environment, triggering a severe threat to living species. With their complex chemical nature and the intricacy involved in the removal process in mind, the present work investigates the performance of commercially available polyamide thin-film composite tubular nanofiltration (NF) membranes (AFC 40 and AFC 80) in removing polluting pharmaceutical drugs, namely caffeine, paracetamol and naproxen. The structural parameters of the NF membranes were estimated by water permeability measurements and retention measurements with aqueous solutions of organic, uncharged (glycerol) solutes. The effect of various operating conditions on the retention of solutes by the AFC 40 and AFC 80 membranes, such as applied transmembrane pressure, tangential feed flow velocity, feed solution concentration and ionic strength, were evaluated. It was found that the rejection of drugs was directly proportional to transmembrane pressure and feed flow rate. Due to the size difference between caffeine (MW = 194.9 g/mol), naproxen (MW = 230.2 g/mol) and paracetamol (MW = 151.16 g/mol), the AFC 40 membrane proved to be efficient for caffeine and naproxen, with rejection efficiencies of 88% and 99%, respectively. In contrast, the AFC 80 membrane proved to be better for paracetamol, with a rejection efficiency of 96% (and rejection efficiency of 100% for caffeine and naproxen). It was also observed that the rejection efficiency of the AFC 80 membrane did not change with changes in external operating conditions compared to the AFC 40 membrane. The membrane performance was predicted using the Spiegler-Kedem model based on irreversible thermodynamics, which was successfully used to explain the transport mechanism of solutes through the AFC 40 and AFC 80 membranes in the NF process.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20402 - Chemical process engineering

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Membranes

ISSN

2077-0375

e-ISSN

2077-0375

Volume of the periodical

12

Issue of the periodical within the volume

5

Country of publishing house

CH - SWITZERLAND

Number of pages

16

Pages from-to

528

UT code for WoS article

000801405600001

EID of the result in the Scopus database

2-s2.0-85130710544