Application of Positron Emission Tomography to Aerosol Transport Research in a Model of Human Lungs

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F12%3APU100717" target="_blank" >RIV/00216305:26210/12:PU100717 - isvavai.cz</a>
Alternative codes found
RIV/00209805:_____/13:#0000599
Result on the web
<a href="https://www.epj-conferences.org/articles/epjconf/abs/2013/06/epjconf_efm2013_01060/epjconf_efm2013_01060.html" target="_blank" >https://www.epj-conferences.org/articles/epjconf/abs/2013/06/epjconf_efm2013_01060/epjconf_efm2013_01060.html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1051/epjconf/20134501060" target="_blank" >10.1051/epjconf/20134501060</a>

Result language
angličtina
Original language name
Application of Positron Emission Tomography to Aerosol Transport Research in a Model of Human Lungs
Original language description
Positron Emission Tomography (PET) is a convenient method for measurement of aerosol deposition in complex models of lungs. It allows not only the evaluation of regional deposition characteristics but also precisely detects deposition hot spots. The method is based on a detection of a pair of annihilation photons moving in opposite directions as a result of positron – electron interaction after the positron emission decay of a suitable radioisotope. Liquid di(2-ethylhexyl) sebacate (DEHS) particles tagged with fluorine-18 as a radioactive tracer were generated by condensation monodisperse aerosol generator. Aerosol deposition was measured for three different inhalation flowrates and for two sizes of particles. Combination of PET with Computed Tomography (CT) in one device allowed precise localisation of particular segments of the model. The results proved correlation of deposition efficiency with Stokes number, which means that the main deposition mechanism is inertial impaction. As a next task the methodology for tagging the solid aerosol particles with radioactive tracer will be developed and deposition of porous and fiber aerosols will be measured.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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