Development and use of non-FDG PET radiopharmaceuticals at the Masaryk Memorial Cancer Institute

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46356088%3A_____%2F12%3A%230001243" target="_blank" >RIV/46356088:_____/12:#0001243 - isvavai.cz</a>

Alternative codes found

RIV/00209805:_____/12:#0000308

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Development and use of non-FDG PET radiopharmaceuticals at the Masaryk Memorial Cancer Institute

Original language description

Positron Emission Tomography (PET) is a convenient method for measurement of aerosol deposition in complex models of lungs. It allows not only the evaluation of regional deposition characteristics but also precisely detects deposition hot spots. The method is based on a detection of a pair of annihilation photons moving in opposite directions as a result of positron - electron interaction after the positron emission decay of a suitable radioisotope. Liquid di(2-ethylhexyl) sebacate (DEHS) particles tagged with fluorine-18 as a radioactive tracer were generated by condensation monodisperse aerosol generator. Aerosol deposition was measured for three different inhalation flowrates and for two sizes of particles. Combination of PET with Computed Tomography (CT) in one device allowed precise localisation of particular segments of the model. The results proved correlation of deposition efficiency with Stokes number, which means that the main deposition mechanism is inertial impaction. As a

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FS - Medical facilities, apparatus and equipment

OECD FORD branch

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Project

<a href="/en/project/ED2.1.00%2F03.0101" target="_blank" >ED2.1.00/03.0101: Regional Centre for Applied Molecular Oncology (RECAMO)</a><br>

Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Klinická onkologie

ISSN

0862-495X

e-ISSN

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Volume of the periodical

25

Issue of the periodical within the volume

S2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

5

Pages from-to

82-86

UT code for WoS article

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EID of the result in the Scopus database

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