Observation of lubrication mechanisms in knee replacement: A pilot study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F19%3APU131064" target="_blank" >RIV/00216305:26210/19:PU131064 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/19:73593097
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2352573818300416" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2352573818300416</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.biotri.2019.02.001" target="_blank" >10.1016/j.biotri.2019.02.001</a>
Alternative languages
Result language
angličtina
Original language name
Observation of lubrication mechanisms in knee replacement: A pilot study
Original language description
The present study introduces a unique experimental approach for in situ observation of lubricant film formation in knee joint replacements. A knee joint simulator was designed and equipped with optical module based on fluorescent optical method for film thickness observation. The contact between the femoral knee metal implant and real-shaped polymer insert mimicking actual contact nature is observed. The shape of the polymer insert was fabricated with respect to the shape of original polyethylene insert to ensure corresponding contact conformity. Simple solutions of albumin and γ-globulin proteins as well as its mixture were used while the film thickness was studied as a function of time considering simplified flexion/extension motion with variable load over the cycle. Adequate fluorescent markers were employed enabling to observe one particular protein during each measurement. The results showed a clear importance of the interaction of proteins since the mixtures showed different results compared to simple solutions. Especially considering albumin protein, its behaviour was substantially affected by adding γ-globulin. Moreover, a satisfactory compliance with previous findings related to hip joint lubrication in terms of the behaviour of both proteins was found. Finally, the motivation for future experimental work is highlighted.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
20301 - Mechanical engineering
Result continuities
Project
<a href="/en/project/LTAUSA17150" target="_blank" >LTAUSA17150: The effect of tribological processes on the durability of knee joint replacements</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biotribology
ISSN
2352-5738
e-ISSN
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Volume of the periodical
17
Issue of the periodical within the volume
2019
Country of publishing house
GB - UNITED KINGDOM
Number of pages
7
Pages from-to
1-7
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85061051598