Beneficial osseointegration effect of hydroxyapatite coating on cranial implant - FEM investigation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F21%3APU141311" target="_blank" >RIV/00216305:26210/21:PU141311 - isvavai.cz</a>
Alternative codes found
RIV/61389021:_____/21:00544748
Result on the web
<a href="https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0254837" target="_blank" >https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0254837</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0254837" target="_blank" >10.1371/journal.pone.0254837</a>
Alternative languages
Result language
angličtina
Original language name
Beneficial osseointegration effect of hydroxyapatite coating on cranial implant - FEM investigation
Original language description
A firm connection of the bone-implant-fixation system is of utmost importance for patients with cranial defects. In order to improve the connection reliability, the current research focuses on finding the optimal fixation method, as well as selection of the implant manufacturing methods and the used materials. For the latter, implementation of bioactive materials such as hydroxyapatite or other calcium phosphates has also been considered in the literature. The aim of this study was to investigate the effect of gradual osseointegration on the biomechanical performance of cranial Ti6Al4V implants with a deposited HA coating as the osseointegration agent. This effect was assessed by two different computational approaches using finite element method (FEM) modeling. The values of key input parameters necessary for FEM were obtained from experimental plasma spray deposition of HA layers onto Ti6Al4V samples. Immediately upon implantation, the HA layer at the bone-implant contact area brought only a slight decrease in the values of von Mises stress in the implant and the micro-screws when compared to a non-coated counterpart; importantly, this was without any negative trade-off in other important characteristics. The major benefit of the HA coatings was manifested upon the modeled osseointegration: the results of both approaches confirmed a significant reduction of investigated parameters such as the total implant displacements (reduced from 0.050 mm to 0.012 mm and 0.002 mm while using Approach I and II, respectively) and stresses (reduced from 52 MPa to 10 MPa and 1 MPa) in the implanted components in comparison to non-coated variant. This is a very promising result for potential use of thermally sprayed HA coatings for cranial implants.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10700 - Other natural sciences
Result continuities
Project
<a href="/en/project/GA19-10246S" target="_blank" >GA19-10246S: Deposition mechanisms and properties of multiphase plasma sprayed coatings prepared with liquid feedstocks</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PLOS ONE
ISSN
1932-6203
e-ISSN
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Volume of the periodical
16
Issue of the periodical within the volume
7
Country of publishing house
US - UNITED STATES
Number of pages
16
Pages from-to
„e0254837“-„e0254837“
UT code for WoS article
000678122000004
EID of the result in the Scopus database
2-s2.0-85110779980