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Beneficial osseointegration effect of hydroxyapatite coating on cranial implant FEM investigation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389021%3A_____%2F21%3A00544748" target="_blank" >RIV/61389021:_____/21:00544748 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216305:26210/21:PU141311

  • Result on the web

    <a href="https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0254837" target="_blank" >https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0254837</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1371/journal.pone.0254837" target="_blank" >10.1371/journal.pone.0254837</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Beneficial osseointegration effect of hydroxyapatite coating on cranial implant FEM investigation

  • Original language description

    A firm connection of the bone-implant-fixation system is of utmost importance for patients with cranial defects. In order to improve the connection reliability, the current research focuses on finding the optimal fixation method, as well as selection of the implant manufacturing methods and the used materials. For the latter, implementation of bioactive materials such as hydroxyapatite or other calcium phosphates has also been considered in the literature. The aim of this study was to investigate the effect of gradual osseointegration on the biomechanical performance of cranial Ti6Al4V implants with a deposited HA coating as the osseointegration agent. This effect was assessed by two different computational approaches using finite element method (FEM) modeling. The values of key input parameters necessary for FEM were obtained from experimental plasma spray deposition of HA layers onto Ti6Al4V samples. Immediately upon implantation, the HA layer at the bone-implant contact area brought only a slight decrease in the values of von Mises stress in the implant and the micro-screws when compared to a non-coated counterpart - importantly, this was without any negative trade-off in other important characteristics. The major benefit of the HA coatings was manifested upon the modeled osseointegration: the results of both approaches confirmed a significant reduction of investigated parameters such as the total implant displacements (reduced from 0.050 mm to 0.012 mm and 0.002 mm while using Approach I and II, respectively) and stresses (reduced from 52 MPa to 10 MPa and 1 MPa) in the implanted components in comparison to non-coated variant. This is a very promising result for potential use of thermally sprayed HA coatings for cranial implants.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    20501 - Materials engineering

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    PLoS ONE

  • ISSN

    1932-6203

  • e-ISSN

    1932-6203

  • Volume of the periodical

    16

  • Issue of the periodical within the volume

    July

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    16

  • Pages from-to

    e0254837

  • UT code for WoS article

    000678122000004

  • EID of the result in the Scopus database

    2-s2.0-85110779980