Deposition of rigid glass fibres inside a replica of female airways

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F24%3APU155353" target="_blank" >RIV/00216305:26210/24:PU155353 - isvavai.cz</a>
Result on the web
<a href="http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2024.pdf" target="_blank" >http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2024.pdf</a>
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
Deposition of rigid glass fibres inside a replica of female airways
Original language description
Inhaled fibrous microparticles can pose serious health risks, which have led to significant attention in the last decades. Fibres, particularly the smaller ones, can penetrate deeply into the lungs and reach the alveoli. Their elongated shape causes this. Usual inhalable spherical drugs in the size range of 5 – 10 µm have difficulty reaching the deeper regions of the lung. Thus, the fibrous shape may provide a solution for delivery in these regions, but the mechanics of inhaled fibre flow are more complex compared to spherical particles. Therefore, it is important to understand how specific parameters (e.g. breathing flowrate, dimensions of fibres) influence the flow and deposition of fibrous aerosols in the human airways.
Czech name
—
Czech description
—

Project
<a href="/en/project/GA22-20357S" target="_blank" >GA22-20357S: Measurement and computational simulation of transport of fibrous aerosols in high velocity gradient flow and interaction of fibres with a wall</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)