Influence of ischemia on left ventricular depolarization in isolated rabbit hearts perfused according to Langendorff

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F09%3APU81293" target="_blank" >RIV/00216305:26220/09:PU81293 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

čeština

Original language name

Influence of ischemia on left ventricular depolarization in isolated rabbit hearts perfused according to Langendorff

Original language description

The aim of this study was to search for relation between electrical activity recorded from whole isolated heart and simultaneously from one cell. The QRS complex of elec-trogram (ECG) corresponds to the depolarization of the ven-tricles. The depolarization propagation is shown by monopha-sic action potential (MAP) recorded at appointed place during experiment. Electrogram changes observed during ischemia should be accounted for changes on cellular level. MAPs and ECG were recorded simultaneously. The activation time (AT), defined as distance from the earliest QRS deflection to MAP upstroke, changes with duration of ischemia. The excitement propagation and conduction in ischemic heart takes longer time in comparison to non-ischemic myocardium.

Czech name

Influence of ischemia on left ventricular depolarization in isolated rabbit hearts perfused according to Langendorff

Czech description

The aim of this study was to search for relation between electrical activity recorded from whole isolated heart and simultaneously from one cell. The QRS complex of elec-trogram (ECG) corresponds to the depolarization of the ven-tricles. The depolarization propagation is shown by monopha-sic action potential (MAP) recorded at appointed place during experiment. Electrogram changes observed during ischemia should be accounted for changes on cellular level. MAPs and ECG were recorded simultaneously. The activation time (AT), defined as distance from the earliest QRS deflection to MAP upstroke, changes with duration of ischemia. The excitement propagation and conduction in ischemic heart takes longer time in comparison to non-ischemic myocardium.

Type

D - Article in proceedings

CEP classification

JD - Use of computers, robotics and its application

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

IFMBE Proceeding, Volume 25, World Congress on Medical Physics and Biomedical Engineering

ISBN

978-3-642-03897-6

ISSN

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e-ISSN

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Number of pages

4

Pages from-to

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Publisher name

Springer Berlin

Place of publication

Munich, Germany

Event location

Mnichov

Event date

Sep 7, 2009

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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