Effects of Voltage-Sensitive Dye di-4-ANEPPS on Isolated Rat Heart Electrogram

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F11%3APU94172" target="_blank" >RIV/00216305:26220/11:PU94172 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Effects of Voltage-Sensitive Dye di-4-ANEPPS on Isolated Rat Heart Electrogram
Original language description
Mapping of cardiac electrical activity from Langendorff-perfused hearts using the voltage-sensitive dye (VSD) di-4-ANEPPS has yielded important new information. However, data about response of the heart to staining with VSD are scarce. Voltage-sensitivedye di-4-ANEPPS is currently used in our laboratory for recording of monophasic action potentials by optical method in isolated hearts. The most often used species in basic cardiology is the rat heart. In order to describe in more detail the response ofthe heart tissue exposed to di-4-ANEPPS, heart rate changes and arrhythmia-preceding parameters in isolated rat heart electrogram during staining with di-4-ANEPPS and washout period, were followed.
Czech name
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Czech description
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Project
<a href="/en/project/GA102%2F07%2F1473" target="_blank" >GA102/07/1473: Optical Methods for Registration of Heart Electrical Potentials and Calcium Concentration with Laser Stabilization</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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