Protinádorové léčivo Doxorubicin a jeho IN VIVO analýza fluorescenční mikroskopií

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F12%3APU100799" target="_blank" >RIV/00216305:26220/12:PU100799 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

čeština

Original language name

Anticancer drug Doxorubicin and IN VIVO analysis by fluorescence microscopy

Original language description

Doxorubicin is a cytostatic drug used in cancer therapy; however its cardiotoxicity is limiting the clinical application. On the other hand, it has fluorescence properties, and therefore it is suitable for monitoring by fluorescence microscopy. In this study fluorescence microscopy was used for imaging of doxorubicin interactions with Staphylococcus aureus and BY-2 cells. Bacterial and BY-2 cells were stained by doxorubicin, and the influence of doxorubicin on cells viability was investigated.

Czech name

Anticancer drug Doxorubicin and IN VIVO analysis by fluorescence microscopy

Czech description

Doxorubicin is a cytostatic drug used in cancer therapy; however its cardiotoxicity is limiting the clinical application. On the other hand, it has fluorescence properties, and therefore it is suitable for monitoring by fluorescence microscopy. In this study fluorescence microscopy was used for imaging of doxorubicin interactions with Staphylococcus aureus and BY-2 cells. Bacterial and BY-2 cells were stained by doxorubicin, and the influence of doxorubicin on cells viability was investigated.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

—

Project

<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

CHEMagazín

ISSN

1210-7409

e-ISSN

—

Volume of the periodical

2012

Issue of the periodical within the volume

5

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

3

Pages from-to

8-10

UT code for WoS article

—

EID of the result in the Scopus database

—