Identification of horizontal genes transfer elements across strains inhabiting the same niche using pan-genome analysis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F22%3APU145790" target="_blank" >RIV/00216305:26220/22:PU145790 - isvavai.cz</a>
Result on the web
<a href="https://www.eeict.cz/eeict_download/archiv/sborniky/EEICT_2022_sbornik_1_v2.pdf" target="_blank" >https://www.eeict.cz/eeict_download/archiv/sborniky/EEICT_2022_sbornik_1_v2.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Identification of horizontal genes transfer elements across strains inhabiting the same niche using pan-genome analysis
Original language description
Tracing horizontal gene flux across strains in farm animals is one of the important steps for research focused on detection and genomic enzymology of genes conferring antibiotic resistance. In this study, we have built the comprehensive computational methodology for the detection of horizontal genes transfer elements via pan-genome analysis. In total, 133 anaerobes isolated from chicken gastrointestinal tract were examined for the presence of traits of horizontal transfer. The shared genes from all isolates, so called core genome genes were identified and characterised in order to assign the function to the gene within individual bacterial cell and within community of cells. This study provides an evidence that horizontal transmission frequently occurs not only between closely related bacteria, but also between distant taxonomical groups. Hence chickens are known primary reservoirs of antibiotic resistance genes, and the dissemination of these genes to other bacterial pathogens often leads to life-thr
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Result continuities
Project
<a href="/en/project/GA22-16786S" target="_blank" >GA22-16786S: Horizontal gene transfer network in chicken gut microbiome: detection and prediction of antibiotic resistome and mobilome</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů