The Effect of Tissue Physiological Variablity on Transurethral Ultrasound Therapy of the Prostate
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26230%2F18%3APU130697" target="_blank" >RIV/00216305:26230/18:PU130697 - isvavai.cz</a>
Result on the web
<a href="https://ieeexplore.ieee.org/document/8513548" target="_blank" >https://ieeexplore.ieee.org/document/8513548</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1109/EMBC.2018.8513548" target="_blank" >10.1109/EMBC.2018.8513548</a>
Alternative languages
Result language
angličtina
Original language name
The Effect of Tissue Physiological Variablity on Transurethral Ultrasound Therapy of the Prostate
Original language description
Therapeutic ultrasound is an established modality which can be used for minimally invasive treatment of prostate cancer. Computational simulation models were used to study the effect of natural physiological variations in tissue parameters on the efficacy of therapeutic ultrasound treatment in the prostate. The simulations were conducted on a clinical ultrasound therapy system using patient computed tomography (CT) data. The values of attenuation, perfusion, specific heat capacity and thermal conductivity were changed within their biological ranges to determine their effect on peak temperature and thermal dose volume. Increased attenuation was found to have the biggest effect on peak temperature with a 6.9% rise. The smallest effect was seen with perfusion with 0.2% variation in peak temperature. Thermal dose was mostly affected by specific heat capacity which showed a 20.7% increase in volume with reduced heat capacity. Thermal conductivity had the smallest effect on thermal dose with up to 2.1% increase in the volume with reduced thermal conductivity. These results can be used to estimate the expected interpatient variation during the therapeutic ultrasound treatment of the prostate.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Result continuities
Project
<a href="/en/project/LQ1602" target="_blank" >LQ1602: IT4Innovations excellence in science</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Proceedings of 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
ISBN
978-1-5386-3646-6
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
5701-5704
Publisher name
Institute of Electrical and Electronics Engineers
Place of publication
Honolulu, HI
Event location
Honolulu, HI, USA
Event date
Jul 17, 2018
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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