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DEMIS: Electron Microscopy Image Stitching using Deep Learning Features and Global Optimisation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26230%2F25%3APU155128" target="_blank" >RIV/00216305:26230/25:PU155128 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.scitepress.org/publishedPapers/2025/133149/pdf/index.html" target="_blank" >https://www.scitepress.org/publishedPapers/2025/133149/pdf/index.html</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    DEMIS: Electron Microscopy Image Stitching using Deep Learning Features and Global Optimisation

  • Original language description

    Accurate stitching of overlapping image tiles is essential for reconstructing large-scale Electron Microscopy (EM) images during Whole Slide Imaging. Current stitching approaches rely on handcrafted features and translation-only global alignment based on Minimum Spanning Tree (MST) construction. This results in suboptimal global alignment since it neglects rotational errors and works only with transformations estimated from pairwise feature matches, discarding valuable information tied to individual features. Moreover, handcrafted features may have trouble with repetitive textures. Motivated by the limitations of current methods and recent advancements in deep learning, we propose DEMIS, a novel EM image stitching method. DEMIS uses Local Feature TRansformer (LoFTR) for image matching, and optimises translational and rotational parameters directly at the level of individual features. For evaluation and training, we create EM424, a synthetic dataset generated by splitting high-resolution EM

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů