Turbidimetry and Fluorescence Study of Effect of Hyaluronan Addition to Cationic Micellar Solution
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F16%3APU120312" target="_blank" >RIV/00216305:26310/16:PU120312 - isvavai.cz</a>
Result on the web
<a href="http://www.ipfdd.de/fileadmin/user_upload/oea/00_Tagungsband_ESOPS20_2016-09-15.pdf" target="_blank" >http://www.ipfdd.de/fileadmin/user_upload/oea/00_Tagungsband_ESOPS20_2016-09-15.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Turbidimetry and Fluorescence Study of Effect of Hyaluronan Addition to Cationic Micellar Solution
Original language description
Hyaluronan as negatively charged polyelectrolyte can interact with positively charged surfactant micelles via electrostatic interactions to form core-shell like aggregates. These self-assembly systems can solubilize hydrophobic active substances and therefore, they are potential carriers in drug delivery applications. This study deals with electrostatic association of cationic micelles of CTAB or Septonex with hyaluronan. The cationic micelle/hyaluronan complexes were studied using turbidimetry and fluorescence spectroscopy method. Turbidimetric titration was chosen as an indicator of the loss of transmitted light intensity due to the scattering effect of particles associated from hyaluronan and surfactant in it. Fluorescent probe pyrene was selected for spectroscopy experiments because of its unique sensitivity to polarity of the medium, so this fluorescence method was used as an indicator of presence of hydrophobic domains in the system. Effect of components concentration and molecular weight of hya
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LO1211" target="_blank" >LO1211: Materials Research Centre at FCH BUT- Sustainability and Development</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů