The Use of Bioactive Compounds and Their Encapsulation into Liposomes to Increase the Effectiveness and Control Release

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F18%3APU130885" target="_blank" >RIV/00216305:26310/18:PU130885 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The Use of Bioactive Compounds and Their Encapsulation into Liposomes to Increase the Effectiveness and Control Release
Original language description
The aim of this work is to encapsulate microbial compounds, some plant extracts and also model hydrophilic and hydrophobic substances. Chosen components were encapsulated into liposomes. Particle size and distributions of liposomes were analyzed by dynamic light scattering and their stability by using zeta potential. Spectrophotometric methods were used to measure encapsulation efficiency and to characterize the chosen plant extracts by its amount of total polyphenols, flavonoids and antioxidant activity. Chosen samples were analyzed for their antimicrobial activity and cytotoxicity. Serratia marcescens, Escherichia coli as gram-negative bacterias, Micrococcus luteus as gram-positive bacteria and fungal strain (Candida glabrata) were used to test antimicrobial activity. Human keratinocytes and mouse melanoma cells were used to cytotoxicity determination.
Czech name
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Czech description
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Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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