Functionalized nanofibers with immobilized liposome particles
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F22%3APU146751" target="_blank" >RIV/00216305:26310/22:PU146751 - isvavai.cz</a>
Result on the web
<a href="https://www.icct.cz/cs/program/book-of-abstracts" target="_blank" >https://www.icct.cz/cs/program/book-of-abstracts</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Functionalized nanofibers with immobilized liposome particles
Original language description
Wound healing requires suitable environment to promote healing process. Therefore, treatment and management of wounds largely depends on the dressing material, that provides surface protection, drug delivery and allows tissue regeneration. Presented work is focused on preparation and further characterization of PHB nanofibers with immobilized PHB-liposome particles. Nanomaterials were functionalized by broad-spectrum antibiotic drug ampicillin. Combined nanostructures were prepared as novel potential wound dressings. Scanning electron microscopy and fluorescence microscopy were used to observe structure of prepared combined nanofiber-nanoparticle mats. Materials were further tested for the encapsulation efficiency and in vitro release of incorporated drug into model environment by spectrophotometric and chromatographic methods. Particle´s size and colloid stability was defined by dynamic light scattering and zeta-potential. The antimicrobial activity against selected strains of gram-positive and gram-
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
21001 - Nano-materials (production and properties)
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů