Mucoadhesive injectable hydrogel carriers enriched with encapsulated pro-healing protein for hard-to-heal oral wounds
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F22%3APU144571" target="_blank" >RIV/00216305:26620/22:PU144571 - isvavai.cz</a>
Result on the web
<a href="http://www.ccsss.cz/index.php/ccsss/issue/view/31/45" target="_blank" >http://www.ccsss.cz/index.php/ccsss/issue/view/31/45</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Mucoadhesive injectable hydrogel carriers enriched with encapsulated pro-healing protein for hard-to-heal oral wounds
Original language description
This work aims to prepare an injectable thermosensitive drug delivery system enriched by biologically active substances to enhance healing. The mucoadhesive matrix was formed by an FDA-approved biocompatible, non-toxic synthetic polymer based on poly(lactide-co-glycolide) and poly(ethylene glycol) (PLGA-PEG-PLGA) copolymer functionalized with itaconic anhydride (ITA) patented by BUT. This polymer system is body thermo-responsive and is suggested for delivering a pro-healing protein – stable fibroblast growth factor-2 (FGF2-STAB® from Enantis L.t.d.), which stimulates re-epithelization and thus promotes overall tissue regeneration.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů