Randomized clinical trial comparing neurological outcomes after carotid endarterectomy or stenting
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F15%3A0104577A" target="_blank" >RIV/00843989:_____/15:0104577A - isvavai.cz</a>
Alternative codes found
RIV/00843989:_____/15:0104577B RIV/00843989:_____/15:E0104577 RIV/61383082:_____/15:#0000362
Result on the web
<a href="http://dx.doi.org/10.1002/bjs.9677" target="_blank" >http://dx.doi.org/10.1002/bjs.9677</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/bjs.9677" target="_blank" >10.1002/bjs.9677</a>
Alternative languages
Result language
angličtina
Original language name
Randomized clinical trial comparing neurological outcomes after carotid endarterectomy or stenting
Original language description
BACKGROUND: Silent infarction in the brain can be detected in around 34 per cent of patients after carotid endarterectomy (CEA) and 54 per cent after carotid angioplasty and stenting (CAS). This study compared the risk of new infarctions in the brain in patients undergoing CEA or CAS. METHODS: Consecutive patients with internal carotid artery (ICA) stenosis exceeding 70 per cent were screened for inclusion in this prospective study. Patients with indications for intervention, and eligible for both methods, were allocated randomly to CEA or CAS. Neurological examination, cognitive function tests and MRI of the brain were undertaken before and 24?h after intervention. RESULTS: Of 150 randomized patients, 73 (47 men; mean age 64·9(7·1) years) underwent CEA and 77 (58 men; 66·4(7·5) years) had CAS. New infarctions on MRI were found more frequently after CAS (49 versus 25 per cent; P?=?0·002). Lesion volume was also significantly greater after CAS (P?=?0·010). Multiple logistic regression analyses identified intervention in the right ICA as the only independent predictor of brain infarction (odds ratio 2·10, 95 per cent c.i. 1·03 to 4·25; P?=?0·040). Stroke or transient ischaemic attack occurred in one patient after CEA and in two after CAS. No significant differences were found in cognitive test results between the groups. CONCLUSION: These data confirm a higher risk of silent infarction in the brain on MRI after CAS in comparison with CEA, but without measurable change in cognitive function.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
British Journal of Surgery
ISSN
0007-1323
e-ISSN
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Volume of the periodical
102
Issue of the periodical within the volume
n. 3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
"p. 194-201"
UT code for WoS article
000348991400006
EID of the result in the Scopus database
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