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Determination of major phenolic compounds in apples: Part I-Optimization of high-performance liquid chromatography separation with diode array detection

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F25271121%3A_____%2F18%3AN0000010" target="_blank" >RIV/25271121:_____/18:N0000010 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11160/18:10377488

  • Result on the web

    <a href="http://dx.doi.org/10.1002/jssc.201800302" target="_blank" >http://dx.doi.org/10.1002/jssc.201800302</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/jssc.201800302" target="_blank" >10.1002/jssc.201800302</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Determination of major phenolic compounds in apples: Part I-Optimization of high-performance liquid chromatography separation with diode array detection

  • Original language description

    The separation of seven phenolic compounds including gallic acid, chlorogenic acid, epicatechin, quercitrin, rutin, phloridzin, and phloretin present in apple peel and pulp and differing in elution properties has been optimized using high-performance liquid chromatography with diode array detection. Several stationary phases were tested to achieve the efficient separation of phenolic compounds in fruit extracts and C18 was found to be the most efficient. Core-shell and fully porous C18 packings were assessed with respect to the complex composition of the fruit extracts. The developed high-performance liquid chromatography method comprised gradient elution in which mobile phase A was water at pH 2.8 adjusted with acetic acid and B was acetonitrile. The gradient shape was the following: 0 min 95% A/5% B, 2.5 min 85% A/15% B, 12 min 50% A/50% B, 15 min 95% A/5% B. The flow rate was 1 mL/min, injection volume 10 mu L, and UV detection at 255, 280, 320, and 365 nm was applied. Our method was validated for both C18 core-shell and fully porous packings. The resolution 6.2-14.8, symmetry 0.99-1.34, peak capacity 18-60, peak area repeatability 0.45-1.00% relative standard deviation, calibration range 0.125-5 mg/mL (0.2510 mg/mL for chlorogenic acid and rutin), correlation coefficients of calibration curve 0.9976-0.9997, and accuracy evaluated as recovery 95.56-107.54% were determined for the core-shell column.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Separation Science

  • ISSN

    1615-9306

  • e-ISSN

  • Volume of the periodical

    41

  • Issue of the periodical within the volume

    15

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    9

  • Pages from-to

    3042-3050

  • UT code for WoS article

    000440842600004

  • EID of the result in the Scopus database

    2-s2.0-85051193553