Acetylcholinesterase based elektrochemical biodsenzor using indoxylacetate as a substance for fast assay of neurotixic compounds

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F25766872%3A_____%2F12%3A%230000081" target="_blank" >RIV/25766872:_____/12:#0000081 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

čeština

Original language name

Acetylcholinesterase based elektrochemical biodsenzor using indoxylacetate as a substance for fast assay of neurotixic compounds

Original language description

Acetylcholinesterase (AChE) is an enzyme terminating neurotransmission in cholinergic nervous system. It is targeted by several drugs and toxins. From a toxicological point of view, pesticides and nerve agents are probably the most toxic compounds inhibiting AChE activity. On the account of the enzyme inhibition, AChE is suitable for an in vitro assay of inhibitors and analytical devices such as biosensors are known to work on principle of recording of AChE residual activity. Here reported experiment isbased on previously performed colorimetric dipsticks.

Czech name

Acetylcholinesterase based elektrochemical biodsenzor using indoxylacetate as a substance for fast assay of neurotixic compounds

Czech description

Acetylcholinesterase (AChE) is an enzyme terminating neurotransmission in cholinergic nervous system. It is targeted by several drugs and toxins. From a toxicological point of view, pesticides and nerve agents are probably the most toxic compounds inhibiting AChE activity. On the account of the enzyme inhibition, AChE is suitable for an in vitro assay of inhibitors and analytical devices such as biosensors are known to work on principle of recording of AChE residual activity. Here reported experiment isbased on previously performed colorimetric dipsticks.

Type

D - Article in proceedings

CEP classification

KA - Militarism

OECD FORD branch

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Project

<a href="/en/project/VF20122014023" target="_blank" >VF20122014023: Detection of nerve agents using electrochemical biosensor</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

International Jpournal of Elektrochemical Sciennce

ISBN

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ISSN

1452-3981

e-ISSN

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Number of pages

4

Pages from-to

4

Publisher name

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Place of publication

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Event location

Paříž

Event date

Jan 1, 2012

Type of event by nationality

EUR - Evropská akce

UT code for WoS article

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