Determination of fetomaternal hemorrhage by flow cytometry and red blood cell alloimunization in pregnancy.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27283933%3A_____%2F15%3AN0000010" target="_blank" >RIV/27283933:_____/15:N0000010 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Determination of fetomaternal hemorrhage by flow cytometry and red blood cell alloimunization in pregnancy.
Original language description
Fetomaternal haemorrhage (FMH) is a state characterized by penetration of fetal red blood cells (RBCs) into maternal circulation before or during delivery. Significant anemia caused by FMH can result in death of the baby before or after birth, or significant illness in the newborn period. Excessive FMH leads to alloimmunization of mother resulting in an increased risk of hemolytic disease of the newborn. Summary/conclusions: FMH with possible clinical significance was founded in 9 cases - excessive FMH only twice. We excluded immunohematologic cause in both cases of excessive FMH. We proved the presence of clinically significant and less significant antibodies caused by FMH after the actual/previous pregnancy or after RBC transfusion. IvIg prophylaxis reduced the overall risk of Rh immunization.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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