Determination of Fetomaternal Hemorrhage by Flow Cytometry and Red Blod Cell Alloimmunization in Pregnancy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27283933%3A_____%2F18%3A00006157" target="_blank" >RIV/27283933:_____/18:00006157 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Determination of Fetomaternal Hemorrhage by Flow Cytometry and Red Blod Cell Alloimmunization in Pregnancy

Original language description

Background and Objectives The aim of the study was the quantitative determination of fetomaternal haemorrhage (FMH) by flow cytometry and red blood cell (RBC) antibody identification in pregnancy. Materials and Methods We present data from a prospective study of 94 women undergoing obstetric interventions from 12/2013 to 07/2014. FMH by flow cytometry using Anti-HbF, RBC antibody screening and ABO RhD blood group by serology was determined in peripheral blood anticoagulated blood samples. The RBC antibody screening was repeated six weeks or later in 51 women. Results Clinically significant FMH was founded in 9 cases of 94. We present 2 cases of excessive FMH. The first case was a spontaneous vaginal delivery at 40th week of pregnancy with a 4.9% FMH. The second case was acute caesarean section at 40th week of pregnancy with a 6.9% FMH. 8 from 94 samples contained RBC antibodies within the first examination immediately after obstetric procedure. 11 from 51 samples contained RBC antibodies within the second examination. Conclusion FMH with possible clinical significance was founded in 9 cases, excessive FMH only twice. We proved the presence of clinically significant and less significant antibodies caused by FMH after the actual or previous pregnancy.

Czech name

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Czech description

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Type

J_ost - Miscellaneous article in a specialist periodical

CEP classification

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OECD FORD branch

30205 - Hematology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Annals of Hematology & Oncology

ISSN

2375-7965

e-ISSN

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Volume of the periodical

5

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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