Determination of Fetomaternal Hemorrhage by Flow Cytometry and Red Blood Cell Alloimmunization in Pregnancy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27283933%3A_____%2F18%3A00005479" target="_blank" >RIV/27283933:_____/18:00005479 - isvavai.cz</a>
Result on the web
<a href="http://www.austinpublishinggroup.com" target="_blank" >http://www.austinpublishinggroup.com</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Determination of Fetomaternal Hemorrhage by Flow Cytometry and Red Blood Cell Alloimmunization in Pregnancy
Original language description
Background and Objectives: The aim of the study was the quantitative determination of Fetomaternal Haemorrhage (FMH) by flow cytometry and Red Blood Cell (RBC) antibody identification in pregnancy. Materials and Methods: We present data from a prospective study of 94 women undergoing obstetric interventions from 12/2013 to 07/2014. FMH by flow cytometry using Anti-HbF, RBC antibody screening and ABO/RhD blood group by serology was determined in peripheral blood anticoagulated blood samples. The RBC antibody screening was repeated six weeks or later in 51 women. Results: Clinically significant FMH was founded in 9 cases of 94. We present 2 cases of excessive FMH. The first case was a spontaneous vaginal delivery at 40th week of pregnancy with a 4.9% FMH. The second case was acute caesarean section at 40th week of pregnancy with a 6.9% FMH. 8 from 94 samples contained RBC antibodies within the first examination immediately after obstetric procedure. 11 from 51 samples contained RBC antibodies within the second examination. Conclusion: FMH with possible clinical significance was founded in 9 cases, excessive FMH only twice. We proved the presence of clinically significant and less significant antibodies caused by FMH after the actual or previous pregnancy.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30230 - Other clinical medicine subjects
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů