The fat mass, estimated glomerular filtration rate, and chronic inflammation in type 2 diabetic patients
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27661989%3A_____%2F20%3A10002759" target="_blank" >RIV/27661989:_____/20:10002759 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17110/20:A210259H RIV/70883521:28110/20:63526107 RIV/70883521:28610/20:63526107
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/epdf/10.1002/jcla.23229" target="_blank" >https://onlinelibrary.wiley.com/doi/epdf/10.1002/jcla.23229</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jcla.23229" target="_blank" >10.1002/jcla.23229</a>
Alternative languages
Result language
angličtina
Original language name
The fat mass, estimated glomerular filtration rate, and chronic inflammation in type 2 diabetic patients
Original language description
Background The aim of the study was to analyze the degree of obesity and its associations with age, gender, inflammation, an estimated glomerular filtration rate (eGFR), and liver function in type 2 diabetes mellitus (T2DM) patients.Methods A total of 874 consecutive adult Caucasian T2DM patients from outpatient diabetic clinic were included in the study. The relative fat mass (RFM) and body mass index (BMI) were used as obesity markers. Serum creatinine and cystatin C were used for the GFR estimation. Serum high-sensitive C-reactive protein (hsCRP) was used as the indicator of inflammation.Results The median, interquartile range (IQR) of RFM in females was higher than that in males (44.8 (42.3-47.2) % vs 31.3 (28.8-34.1) %, respectively; P < .0001). The median (IQR) of BMI in females was no higher than that in males (30 (27-34) kg/m(2) vs 30 (27-34), respectively; P = .5152). The obesity prevalence was 99% in males and 98% in females according to RFM. BMI recognized obesity in 51% males and 53% females. RFM was positively associated with hsCRP in both males (r(s) = .296, P < .0001) and females (r(s) = .445, P < .0001). ALT was positively correlated with eGFRcys in both males (r(s) = .379, P < .0001) and females (r(s) = .308, P < .0001).Conclusion The RFM equation leads to higher obesity prevalence compared to BMI. Women have higher RFM compared to men. The kidney function was positively correlated with ALT serum concentrations.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])
Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Clinical Laboratory Analysis
ISSN
0887-8013
e-ISSN
1098-2825
Volume of the periodical
34
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
nestránkováno
UT code for WoS article
000512423000001
EID of the result in the Scopus database
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