Antagonization of neuromuscular blockade by sugammadex vs. neostigmine in patients undergoing robotic-assisted urological procedures - effect on extubation time and quality of the recovery - monocentric prospective randomized study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13450%2F21%3A43896871" target="_blank" >RIV/44555601:13450/21:43896871 - isvavai.cz</a>
Result on the web
<a href="https://aimjournal.cz/artkey/aim-202104-0001_antagonization-of-neuromuscular-blockade-by-sugammadex-vs-neostigmine-in-patients-undergoing-robotic-8209-ass.php" target="_blank" >https://aimjournal.cz/artkey/aim-202104-0001_antagonization-of-neuromuscular-blockade-by-sugammadex-vs-neostigmine-in-patients-undergoing-robotic-8209-ass.php</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.36290/aim.2021.047" target="_blank" >10.36290/aim.2021.047</a>
Alternative languages
Result language
angličtina
Original language name
Antagonization of neuromuscular blockade by sugammadex vs. neostigmine in patients undergoing robotic-assisted urological procedures - effect on extubation time and quality of the recovery - monocentric prospective randomized study
Original language description
Objective: The aim of the study was to test the hypothesis that the use of sugammadex shortens the time to extubation compared to the use of neostigmine in patients undergoing robotically assisted urological procedures. Design: Monocentric prospective randomized study. Setting: Tertiary Care Hospital. Material and methods: Sixty adult patients undergoing robotic-assisted urological laparoscopic surgery without contrain-dications to the administration of rocuronium, neostigmine and sugammadex, with perioperative monitoring of the depth of neuromuscular blockade. Patients were randomized to the group with antagonization of the neuromuscular blockade with either neostigmine or sugammadex. Primary outcome was time to extubation from injection of the antagonist. Results: Sixty-one patients with ASA I-III were enrolled. The time to extubation was significantly shorter in the sugammadex group compared to neostigmine group: 10; 3.5-35 minutes, 45; 16-88 minutes respectively, p < 0.00001 (data shown as an average; minimum - maximum range). In addition, patients in the sugammadex group were transported significantly faster from the operating room. There were no differences in the quality and rate of recovery in 72 hours postoperatively. Conclusion: Sugammadex statistically significantly accelerated the time from administration to extubation in ASA I-III patients after robotic-assisted urologic laparoscopic surgery compared to neostigmine. Thus, sugammadex significantly accelerated the patients' operating room turn-over time.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30223 - Anaesthesiology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Anesteziologie a intenzivní medicína
ISSN
1214-2158
e-ISSN
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Volume of the periodical
32
Issue of the periodical within the volume
4-5
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
191-196
UT code for WoS article
000751668600001
EID of the result in the Scopus database
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