Design of Polycaprolactone Vascular Grafts

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F14%3A%230003928" target="_blank" >RIV/46747885:24410/14:#0003928 - isvavai.cz</a>

Result on the web

<a href="http://jit.sagepub.com/content/early/2014/06/23/1528083714540701.full.pdf+html" target="_blank" >http://jit.sagepub.com/content/early/2014/06/23/1528083714540701.full.pdf+html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/1528083714540701" target="_blank" >10.1177/1528083714540701</a>

Result language

angličtina

Original language name

Design of Polycaprolactone Vascular Grafts

Original language description

A large number of patients suffer from vascular diseases, resulting in the need for bypass surgery. Since there are still limitations in the replacement of small diameter vascular grafts, the need and demand for developing more desirable grafts is increasing day by day. In this study, polycaprolactone small-diameter (6?mm) vascular grafts were produced successfully using custom-designed electrospinning apparatus. Radial fiber orientation was achieved by increasing the rotational speed of the collector.The morphological, structural, mechanical, and biological properties were examined. The results show that oriented scaffolds with 2??m average fiber diameter provide 1?MPa ultimate tensile strength in the radial direction. The pore size area was found tobe adequate in the oriented samples required for cell proliferation and diffusion through the tunica media. In vitro biocompatibility of the grafts was proven with 3T3 mouse fibroblasts. After cell seeding, the oriented fibers serve as a

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

<a href="/en/project/ED3.1.00%2F14.0306" target="_blank" >ED3.1.00/14.0306: Innovative products and environmental technologies</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Industrial Textiles

ISSN

1530-8057

e-ISSN

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Volume of the periodical

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Issue of the periodical within the volume

June

Country of publishing house

US - UNITED STATES

Number of pages

21

Pages from-to

1-21

UT code for WoS article

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EID of the result in the Scopus database

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