Silica Nanofibers with Immobilized Tetracycline for Wound Dressing

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F16%3A00003699" target="_blank" >RIV/46747885:24410/16:00003699 - isvavai.cz</a>
Alternative codes found
RIV/46747885:24510/16:00003699 RIV/46747885:24530/16:00003699 RIV/46747885:24620/16:00003699
Result on the web
<a href="http://dx.doi.org/10.1155/2016/2485173" target="_blank" >http://dx.doi.org/10.1155/2016/2485173</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2016/2485173" target="_blank" >10.1155/2016/2485173</a>

Result language
angličtina
Original language name
Silica Nanofibers with Immobilized Tetracycline for Wound Dressing
Original language description
Local antibiotic treatment has its justification for superficial infections. The advantage of this treatment is that the antibiotic has effects on bacterial agent directly at the application site. Skin infections which are intended for the local antibiotic treatment are superficial pyoderma, some festering wounds, burns of second and third degree, infected leg ulcers, or decubitus of second and third degree. Tetracyclines are available topical antibiotics with a broad bacterial spectrum. At present, ointments containing tetracycline are also used for the treatment, which rarely can lead to skin sensitization. In this paper, a development of novel nanofibrous material with immobilized tetracycline is presented. Two different methods of immobilized tetracycline quantification onto silica nanofibers are employed. It was proven that the prevailing part of tetracycline was bound weakly by physisorption forces, while the minor part was covalently bound by NH2 groups formed by the preceding functionalization. The silica nanofibers with immobilized tetracycline are promising material for wound dressing applications due to its antibacterial activity; it was proved by tests.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)