Silica Dioxide Nanofiber Based Drug Delivery System with Sustained Release
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24620%2F20%3A00008202" target="_blank" >RIV/46747885:24620/20:00008202 - isvavai.cz</a>
Result on the web
<a href="https://www.confer.cz/nanocon/2019/read/87-silica-dioxide-nanofiber-based-drug-delivery-system-with-sustained-release.pdf" target="_blank" >https://www.confer.cz/nanocon/2019/read/87-silica-dioxide-nanofiber-based-drug-delivery-system-with-sustained-release.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.37904/nanocon.2019.8770" target="_blank" >10.37904/nanocon.2019.8770</a>
Alternative languages
Result language
angličtina
Original language name
Silica Dioxide Nanofiber Based Drug Delivery System with Sustained Release
Original language description
We developed a transdermal drug delivery system containing tetracycline as a model antibiotic for wound healing application. Our previous in vitro tests proved no cytotoxic effect nor antibacterial activity of the silica nanofiber based matrix. This study was designed to evaluate biocompatibility of our nanofiber-antibiotic system via reconstructed human skin model, and to confirm sustained release of the incorporated active compound. Further characterization showed that both moisture vapor permeability and enhanced hydrophilicity of the modified nanofibers remained consistent after functionalization. The summarized results proved that this drug delivery system is a perspective solution in potential medicated sustained release patch for wound healing.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
21001 - Nano-materials (production and properties)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
NANOCON Conference Proceedings - International Conference on Nanomaterials
ISBN
978-808729495-6
ISSN
2694930X
e-ISSN
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Number of pages
6
Pages from-to
336-341
Publisher name
TANGER LTD
Place of publication
Ostrava, Czech Republic
Event location
Brno, Czech Republic
Event date
Jan 1, 2019
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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