Ventilation Inhomogeneity and Bronchial Basement Membrane Changes in Chronic Neutrophilic Airway Inflammation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24510%2F20%3A00007513" target="_blank" >RIV/46747885:24510/20:00007513 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/20:10410765 RIV/00064203:_____/20:10410765
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0012369219341881" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0012369219341881</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.chest.2019.10.023" target="_blank" >10.1016/j.chest.2019.10.023</a>
Alternative languages
Result language
angličtina
Original language name
Ventilation Inhomogeneity and Bronchial Basement Membrane Changes in Chronic Neutrophilic Airway Inflammation
Original language description
In asthma, ventilation inhomogeneity (mean ± SD) was mild (LCI2.5, 9.3 ± 1.4 vs 7.9 ± 0.9 in control subjects; P = .0391), and the RBM thickened (5.26 ± 0.98 μm vs 3.12 ± 0.62 μm in control subjects; P < .0001). No relation between RBM thickness and ventilation inhomogeneity or lavage cytology was found. In CF and PCD, RBM thickness was similar to that in asthma (4.54 ± 0.66 μm and 5.27 ± 1.11 μm, respectively), but ventilation inhomogeneity was significantly higher (LCI2.5, 12.5 ± 2.4 and 11.8 ± 2.5). Both in CF and PCD, RBM thickness correlated with LCI2.5 (r = 0.594, P = .015; r = 0.821, P = .023). In PCD only, RBM thickness was also related to the number of neutrophils in lavage fluid (r = 0.821; P = .023).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30203 - Respiratory systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chest
ISSN
0012-3692
e-ISSN
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Volume of the periodical
157
Issue of the periodical within the volume
Issue 4, April 2020
Country of publishing house
GB - UNITED KINGDOM
Number of pages
11
Pages from-to
779-789
UT code for WoS article
000523616200025
EID of the result in the Scopus database
2-s2.0-85078839023