The Study of Enantioselectivity of All Regioisomers of Mono- Carboxymethyl-a-Cyclodextrins Used as Additives in Capillary Electrophoresis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24620%2F13%3A%230000110" target="_blank" >RIV/46747885:24620/13:#0000110 - isvavai.cz</a>

Result on the web

<a href="http://onlinelibrary.wiley.com/doi/10.1002/jssc.201201144/abstract" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/jssc.201201144/abstract</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jssc.201201144" target="_blank" >10.1002/jssc.201201144</a>

Result language

angličtina

Original language name

The Study of Enantioselectivity of All Regioisomers of Mono- Carboxymethyl-a-Cyclodextrins Used as Additives in Capillary Electrophoresis

Original language description

This work documents the influence of the position of single carboxymethyl group on the ?-cyclodextrin skeleton on the enantioselectivity. These synthesized monosubstituted carboxymethyl cyclodextrin (CD) derivatives, native ?-cyclodextrin, and commercially available carboxymethyl-?-cyclodextrin with degree of substitution approximately 3 were used as additives into the BGE consisting of phosphate buffer at 20 mmol/L concentration, pH 2.5, and several biologically significant low-molecular-mass chiral compounds were enantioseparated by CE. The results indicate that different substituent location on ?-cyclodextrin skeleton has a significant influence on the enantioseparation of the investigated enantiomers. The enantioselectivity of 2I-O-regioisomer wasbetter than with native ?-cyclodextrin. Comparable results to native ?-cyclodextrin were obtained for 6I-O- regioisomer and the enantioselectivity of 3I-O-regioisomer was even worse than with native ?-cyclodextrin. Commercially available

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CC - Organic chemistry

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Separation Science

ISSN

1615-9306

e-ISSN

—

Volume of the periodical

7

Issue of the periodical within the volume

36

Country of publishing house

DE - GERMANY

Number of pages

5

Pages from-to

1270-1274

UT code for WoS article

—

EID of the result in the Scopus database

—