The study of enantioselectivity of all regioisomers of mono-carboxymethyl-b-cyclodextrin used as chiral selectors in CE

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F13%3A43895059" target="_blank" >RIV/60461373:22340/13:43895059 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1002/jssc.201201144" target="_blank" >http://dx.doi.org/10.1002/jssc.201201144</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jssc.201201144" target="_blank" >10.1002/jssc.201201144</a>

Result language

angličtina

Original language name

The study of enantioselectivity of all regioisomers of mono-carboxymethyl-b-cyclodextrin used as chiral selectors in CE

Original language description

This work documents the influence of the position of single carboxymethyl group on the beta-cyclodextrin skeleton on the enantioselectivity. These synthesized monosubstituted carboxymethyl cyclodextrin (CD) derivatives, native beta-cyclodextrin, and commercially available carboxymethyl-beta-cyclodextrin with degree of substitution approximately 3 were used as additives into the BGE consisting of phosphate buffer at 20 mmol/L concentration, pH 2.5, and several biologically significant low-molecular-masschiral compounds were enantioseparated by CE. The results indicate that different substituent location on beta-cyclodextrin skeleton has a significant influence on the enantioseparation of the investigated enantiomers. The enantioselectivity of 2(I)-O-regioisomer was better than with native beta-cyclodextrin. Comparable results to native beta-cyclodextrin were obtained for 6(I)-O-regioisomer and the enantioselectivity of 3(I)-O-regioisomer was even worse than with native beta-cyclodextri

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

—

Project

<a href="/en/project/GAP206%2F12%2F0453" target="_blank" >GAP206/12/0453: Affinity capillary electromigration methods for selective nanoanalysis of biomolecules and investigation of their interactions</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Separation Science

ISSN

1615-9306

e-ISSN

—

Volume of the periodical

36

Issue of the periodical within the volume

7

Country of publishing house

DE - GERMANY

Number of pages

5

Pages from-to

1270-1274

UT code for WoS article

000319865700015

EID of the result in the Scopus database

—