Towards mathematical heart modelling

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23640%2F03%3A00000121" target="_blank" >RIV/49777513:23640/03:00000121 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Towards mathematical heart modelling
Original language description
The aim of this paper is to present the very first results concerning our development of a "heart simulator" in the frame of the ICEMA2 (Images of Cardiac Electro-Mechanical Activity) project. For this purpose a special constitutive law describing behaviour of heart muscle fibres, and hence the active force generation, has been developed, based on the sliding cross-bridge theory. The fibres contract in reaction to the activation parameter related to calcium concentration within the muscle cells.The muscle tissue itself is supposed to be a composite material of an amorphous matrix, passive connective fibres and active muscle fibres. It is described by the model developed by Rohan and Cimrman. This model is enriched by a simple model of heart valves toenable simulations of one or several heart cycles. We demonstrate this on a cylindrical model of left ventricle.
Czech name
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Czech description
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Project
<a href="/en/project/LN00B084" target="_blank" >LN00B084: Research Centre for New Technologies in the Region of West Bohemia</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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