Micronucleus frequency and content in healthy relatives of cancer patients.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F17%3A43896095" target="_blank" >RIV/60076658:12110/17:43896095 - isvavai.cz</a>

Alternative codes found

RIV/68378041:_____/17:00482212

Result on the web

<a href="http://dx.doi.org/10.1080/1354750X.2016.1276627" target="_blank" >http://dx.doi.org/10.1080/1354750X.2016.1276627</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/1354750X.2016.1276627" target="_blank" >10.1080/1354750X.2016.1276627</a>

Result language

angličtina

Original language name

Micronucleus frequency and content in healthy relatives of cancer patients.

Original language description

OBJECTIVE: To compare chromosomal damage in lymphocytes of individuals who did or did not report first-degree relatives with cancer. MATERIALS AND METHODS: Cases and controls (68 each) were matched for sex, age and radon exposure. Chromosomal damage was quantified as frequency of micronucleus-containing cells and proportion of centromere-free micronuclei. RESULTS: Individuals not reporting cancer in their families showed lower values of both the frequency of micronucleus-containing cells (n.s.) and the proportion of centromere-free micronuclei (p &lt; 0.05) in some subgroups, but not in all. CONCLUSION: The chromosomal damage observed may be due to inheritable genomic instability, but environmental influences cannot be excluded.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30304 - Public and environmental health

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomarkers

ISSN

1354-750X

e-ISSN

—

Volume of the periodical

22

Issue of the periodical within the volume

7

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

667-673

UT code for WoS article

000413979200011

EID of the result in the Scopus database

2-s2.0-85010002333