Micronuclei in lymphocytes from currently active uranium miners

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F12%3A00202019" target="_blank" >RIV/68407700:21460/12:00202019 - isvavai.cz</a>

Alternative codes found

RIV/60076658:12110/12:43884462 RIV/00216208:11120/12:43909542

Result on the web

<a href="http://link.springer.com/article/10.1007%2Fs00411-012-0422-0" target="_blank" >http://link.springer.com/article/10.1007%2Fs00411-012-0422-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00411-012-0422-0" target="_blank" >10.1007/s00411-012-0422-0</a>

Result language

angličtina

Original language name

Micronuclei in lymphocytes from currently active uranium miners

Original language description

Micronuclei can be used as markers of past radiation exposure, but only few studies have dealt with uranium miners. In this paper, we report on micronuclei in lymphocytes from individuals currently working at Rožná, Czech Republic, the last functioning uranium mine in the European Union. A modified micronucleus-centromere test was applied to assess the occurrence of micronuclei in stimulated lymphocytes, as well as their content in terms of whole chromosomes or fragments. Compared with unexposed individuals, the miners had higher frequencies of micronucleus-containing lymphocytes and higher percentages of micronuclei without centromeres, and the differences were significant for both parameters (0.74 ? 0.60 vs. 0.50 ? 0.42, p = 0.017 and 49 ? 44 vs. 12? 21, p = 0.0002; means ? standard deviations). There were also significant correlations between one or other of these parameters on the one hand and various dose values on the other, in particular with a 'retrievable' dose, that is, a do

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

<a href="/en/project/2B08001" target="_blank" >2B08001: Biological dosimetry of individuals occupationally exposed to alpha radiation</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Radiation and Environmental Biophysics

ISSN

0301-634X

e-ISSN

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Volume of the periodical

51

Issue of the periodical within the volume

3

Country of publishing house

DE - GERMANY

Number of pages

6

Pages from-to

277-282

UT code for WoS article

000306694000005

EID of the result in the Scopus database

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