All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Frequency of adult type-associated lactase persistence LCT-13910C/T genotypes in the Czech/Slav and Czech Roma/Gypsy populations

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F17%3A43896855" target="_blank" >RIV/60076658:12110/17:43896855 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023001:_____/17:00075951 RIV/68407700:21460/17:00329140

  • Result on the web

    <a href="http://dx.doi.org/10.1590/1678-4685-GMB-2016-0071" target="_blank" >http://dx.doi.org/10.1590/1678-4685-GMB-2016-0071</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1590/1678-4685-GMB-2016-0071" target="_blank" >10.1590/1678-4685-GMB-2016-0071</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Frequency of adult type-associated lactase persistence LCT-13910C/T genotypes in the Czech/Slav and Czech Roma/Gypsy populations

  • Original language description

    Lactase non-persistence (leading to primary lactose intolerance) is a genetically dependent inability to digest lactose in adulthood. As part of the human adaptation to dairying, the human lactase LCT-13910C/T mutation (which propagates adult expression of lactase) developed, spread and participated in the adaptation to dairying. This variant is associated with lactase activity persistence, and its carriers are able to digest lactose. We compared the frequencies of lactase 13910C/T (rs4988235) genotypes in Czechs/Slavs (N = 288) and Czech Gypsies/Roma (N = 300), two ethnically different groups where this polymorphism has not yet been analysed. Allelic frequencies significantly differed between the populations (p &lt; 0.0001). In Czechs/Slavs, the lactase persistence T allele was present in 76% of the individuals, which is in agreement with frequencies among geographically neighbouring populations. In the Czech Gypsy/Roma population, only 27% of the adults were carriers of at least one lactase persistence allele, similar to the Indian population. In agreement with this result, dairy product consumption was reported by 70.5% of Czechs/Slavs and 39.0% of the Czech Gypsy/Roma population. Both in the Czech Gypsy/Roma and in the Czech/Slavs populations, the presence of carriers of the lactase persistence allele was similar in subjects self-reporting the consumption of unfermented/fresh milk, in comparison to the others.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30307 - Nursing

Result continuities

  • Project

    <a href="/en/project/LD14114" target="_blank" >LD14114: Obesity and overweight in Romany minority in the Region of South Bohemia</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Genetics and Molecular Biology

  • ISSN

    1415-4757

  • e-ISSN

  • Volume of the periodical

    40

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    BR - BRAZIL

  • Number of pages

    3

  • Pages from-to

    450-452

  • UT code for WoS article

    000404114600009

  • EID of the result in the Scopus database

    2-s2.0-85021360429