A bite so sweet: the glycobiology interface of tick-host-pathogen interactions

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F18%3A43897692" target="_blank" >RIV/60076658:12310/18:43897692 - isvavai.cz</a>
Alternative codes found
RIV/60077344:_____/18:00498840
Result on the web
<a href="https://parasitesandvectors.biomedcentral.com/track/pdf/10.1186/s13071-018-3062-7" target="_blank" >https://parasitesandvectors.biomedcentral.com/track/pdf/10.1186/s13071-018-3062-7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s13071-018-3062-7" target="_blank" >10.1186/s13071-018-3062-7</a>

Result language
angličtina
Original language name
A bite so sweet: the glycobiology interface of tick-host-pathogen interactions
Original language description
Vector-borne diseases constitute 17% of all infectious diseases in the world; among the blood-feeding arthropods, ticks transmit the highest number of pathogens. Understanding the interactions between the tick vector, the mammalian host and the pathogens circulating between them is the basis for the successful development of vaccines against ticks or the tick-transmitted pathogens as well as for the development of specific treatments against tick-borne infections. A lot of effort has been put into transcriptomic and proteomic analyses; however, the protein-carbohydrate interactions and the overall glycobiology of ticks and tick-borne pathogens has not been given the importance or priority deserved. Novel (bio)analytical techniques and their availability have immensely increased the possibilities in glycobiology research and thus novel information in the glycobiology of ticks and tick-borne pathogens is being generated at a faster pace each year. This review brings a comprehensive summary of the knowledge on both the glycosylated proteins and the glycan-binding proteins of the ticks as well as the tick-transmitted pathogens, with emphasis on the interactions allowing the infection of both the ticks and the hosts by various bacteria and tick-borne encephalitis virus.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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