A bite so sweet: The glycobiology interface of tick-host-pathogen interactions 11 Medical and Health Sciences 1108 Medical Microbiology

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F18%3A00498840" target="_blank" >RIV/60077344:_____/18:00498840 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1186/s13071-018-3062-7" target="_blank" >http://dx.doi.org/10.1186/s13071-018-3062-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s13071-018-3062-7" target="_blank" >10.1186/s13071-018-3062-7</a>

Result language

angličtina

Original language name

A bite so sweet: The glycobiology interface of tick-host-pathogen interactions 11 Medical and Health Sciences 1108 Medical Microbiology

Original language description

Vector-borne diseases constitute 17% of all infectious diseases in the world, among the blood-feeding arthropods, ticks transmit the highest number of pathogens. Understanding the interactions between the tick vector, the mammalian host and the pathogens circulating between them is the basis for the successful development of vaccines against ticks or the tick-transmitted pathogens as well as for the development of specific treatments against tick-borne infections. A lot of effort has been put into transcriptomic and proteomic analyses, however, the protein-carbohydrate interactions and the overall glycobiology of ticks and tick-borne pathogens has not been given the importance or priority deserved. Novel (bio)analytical techniques and their availability have immensely increased the possibilities in glycobiology research and thus novel information in the glycobiology of ticks and tick-borne pathogens is being generated at a faster pace each year. This review brings a comprehensive summary of the knowledge on both the glycosylated proteins and the glycan-binding proteins of the ticks as well as the tick-transmitted pathogens, with emphasis on the interactions allowing the infection of both the ticks and the hosts by various bacteria and tick-borne encephalitis virus.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10606 - Microbiology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Parasites & Vectors

ISSN

1756-3305

e-ISSN

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Volume of the periodical

11

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

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UT code for WoS article

000450479500004

EID of the result in the Scopus database

2-s2.0-85056602505