Dual color triads: synthesis, photophysics and applications in live cell imaging

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F21%3A43903349" target="_blank" >RIV/60076658:12310/21:43903349 - isvavai.cz</a>

Result on the web

<a href="https://pubs.rsc.org/en/content/articlelanding/2021/NJ/D1NJ00900A" target="_blank" >https://pubs.rsc.org/en/content/articlelanding/2021/NJ/D1NJ00900A</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/d1nj00900a" target="_blank" >10.1039/d1nj00900a</a>

Result language

angličtina

Original language name

Dual color triads: synthesis, photophysics and applications in live cell imaging

Original language description

Fluorescent labels and probes constitute an important class of organic materials used in the development of sensor systems and imaging platforms for various chemical and molecular biology applications. In the development of fluorescent labels and probes, multichromic environment-sensitive fluorophores are very important. In this work, novel triad systems, including subphthalocyanine, BODIPY and thiophene/thianaphthene units, were prepared and their molecular structures were identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and H-1 and C-13 NMR spectroscopy. The optical properties of the subphthalocyanine-BODIPY-thiophene/thianaphthene triads were determined using UV-vis absorption and fluorescence (2D and 3D) spectroscopic methods and quantum chemical calculations. The data were analyzed by comparing the results of the final properties to those of the BODIPY- and subphthalocyanine-alone units. The compounds were also evaluated in live cell imaging using a breast cancer cell line. The novel subphthalocyanine-BODIPY-thiophene/thianaphthene triads displayed dual color emission, which is critically important for the development of novel systems particularly in biomedical applications such as bioimaging and cellular sensor systems.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10403 - Physical chemistry

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

New Journal of Chemistry

ISSN

1144-0546

e-ISSN

—

Volume of the periodical

45

Issue of the periodical within the volume

22

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

9984-9994

UT code for WoS article

000651857000001

EID of the result in the Scopus database

2-s2.0-85107631772