Long-lived termite kings and queens activate telomerase in somatic organs

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F21%3A43903650" target="_blank" >RIV/60076658:12310/21:43903650 - isvavai.cz</a>

Alternative codes found

RIV/68081707:_____/21:00541936 RIV/60077344:_____/21:00541906 RIV/61388963:_____/21:00541906 RIV/00216208:11310/21:10426560

Result on the web

<a href="https://royalsocietypublishing.org/doi/10.1098/rspb.2021.0511" target="_blank" >https://royalsocietypublishing.org/doi/10.1098/rspb.2021.0511</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1098/rspb.2021.0511" target="_blank" >10.1098/rspb.2021.0511</a>

Result language

angličtina

Original language name

Long-lived termite kings and queens activate telomerase in somatic organs

Original language description

Kings and queens of termites, like queens of other advanced eusocial insects, are endowed with admirable longevity, which dramatically exceeds the life expectancies of their non-reproducing nest-mates and related solitary insects. In the quest to find the mechanisms underlying the longevity of termite reproductives, we focused on somatic maintenance mediated by telomerase. This ribonucleoprotein is well established for pro-longevity functions in vertebrates, thanks primarily to its ability of telomere extension. However, its participation in lifespan regulation of insects, including the eusocial taxa, remains understudied. Here, we report a conspicuous increase of telomerase abundance and catalytic activity in the somatic organs of primary and secondary reproductives of the termite Prorhinotermes simplex and confirm a similar pattern in two other termite species. These observations stand in contrast with the telomerase downregulation characteristic for most adult somatic tissues in vertebrates and also in solitary insects and non-reproducing castes of termites. At the same time, we did not observe caste-specific differences in telomere lengths that might explain the differential longevity of termite castes. We conclude that although the telomerase activation in termite reproductives is in line with the broadly assumed association between telomerase and longevity, its direct phenotypic impact remains to be elucidated.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10601 - Cell biology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Proceedings of the Royal Society of London Series B - Biological Sciences

ISSN

0962-8452

e-ISSN

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Volume of the periodical

288

Issue of the periodical within the volume

1949

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

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UT code for WoS article

000642210600010

EID of the result in the Scopus database

2-s2.0-85105905108