Effects of Mercury on Oxidative Stress and Gene Expression of Potential Biomarkers in Larvae of the Chinese Rare Minnow Gobiocypris Rarus

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F14%3A43886785" target="_blank" >RIV/60076658:12520/14:43886785 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s00244-014-0034-6" target="_blank" >http://dx.doi.org/10.1007/s00244-014-0034-6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00244-014-0034-6" target="_blank" >10.1007/s00244-014-0034-6</a>

Result language
angličtina
Original language name
Effects of Mercury on Oxidative Stress and Gene Expression of Potential Biomarkers in Larvae of the Chinese Rare Minnow Gobiocypris Rarus
Original language description
Mercury levels have increased in aquatic food webs throughout the world and can be found at toxic levels in some biota. However, the molecular mechanisms and effects of mercuric chloride (Hg2+) remain poorly understood. In the present study, antioxidantparameters (superoxide dismutase, catalase, glutathione peroxidase, and malondialdehyde)-as well as a series of gene expressions, including cortisol receptor (cr), Na+/K+-ATPase (aptase), and prolactin (prl) genes involved in ion-regulatory process, insulin-like growth factor I (igf1) and growth hormone (gh) related to growth rate, as well as heat shock protein70 (hsp70) and metallothionein (mt) used as physiological stress identification-were measured in whole body of Chinese rare minnow larvae (Gobiocypris rarus) after exposure to Hg2+ (0, 0.1, and 0.3 mg/L) for 4 days. Results show that oxidative stress was generated in fish exposed to Hg2+ and that the transcription levels of cr, atpase, gh, hsp70, and mt genes increased in a dose-d
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GL - Fishery
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)