Physiological Responses in Chinese Rare Minnow Larvae Following Exposure to Low-Dose Tributyltin

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F15%3A43888640" target="_blank" >RIV/60076658:12520/15:43888640 - isvavai.cz</a>
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs00128-015-1655-9" target="_blank" >http://link.springer.com/article/10.1007%2Fs00128-015-1655-9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00128-015-1655-9" target="_blank" >10.1007/s00128-015-1655-9</a>

Result language
angličtina
Original language name
Physiological Responses in Chinese Rare Minnow Larvae Following Exposure to Low-Dose Tributyltin
Original language description
In the present study, the antioxidant response and acetylcholinesterase (AChE) activity were measured in Chinese rare minnow larvae (Gobiocypris rarus) after exposure to tributyltin (TBT) (0, 100, 400 and 800 ngL(-1)) for 7 days, as well as the expression of a series of genes, including cr, aptase and prl genes involved in the ion-regulatory process and igfbp3 and gh related to growth rate. Results shows that oxidative stress was generated in fish exposed to TBT, as evidenced by elevated malondialdehydelevels and the inhibition of antioxidant parameters. The activity of acetylcholinesterase (AChE) was also inhibited in fish under higher TBT stress. Moreover, genes involved in ion regulation and growth were affected, based on the regulated transcription of the cr, atpase, gh, prl and igfbp3 genes in the treated groups. The observed effects of TBT upon antioxidant responses and altered expression of genes provides insight into the use of these molecular biomarkers in evaluating mechanis
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
DN - Environmental impact on health
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)