Alteration of Antioxidant Response and Expression of Related Genes by Cadmium in Chinese Rare Minnow Larvae

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F15%3A43888549" target="_blank" >RIV/60076658:12520/15:43888549 - isvavai.cz</a>
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1002/clen.201400113/abstract" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/clen.201400113/abstract</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/clen.201400113" target="_blank" >10.1002/clen.201400113</a>

Result language
angličtina
Original language name
Alteration of Antioxidant Response and Expression of Related Genes by Cadmium in Chinese Rare Minnow Larvae
Original language description
In the present study, antioxidant parameters were measured in whole body of Chinese rare minnow larvae (Gobiocypris rarus) after exposure to Cd2+ (0, 0.5, and 2.5 mg/L) for four days, as well as a series of genes expression, including cortisol receptor(cr), Na+/K+-ATPase (aptase), and prolactin (prl) genes involved in ion-regulatory process, insulin-like growth factor I (igf1) and growth hormone (gh) related to growth rate, as well as heat shock protein 70(hsp70) and metallothionein(mt) used as physiological stress indices. The results showed that oxidative stress was generated in fish exposed to Cd2+ and the transcription of the cr, atpase, gh, hsp70, and mt genes increased in a dose-dependent manner, but two genes expressions, prl and igf1, showed adecrease in the treated groups. The changes in antioxidant responses and the altered genes expression in this study could provide useful information for evaluating the influence mechanisms of cadmium on fish, and could be used as potentia
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
DN - Environmental impact on health
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)