Segregated water observed in a putative fish embryo cryopreservative
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F16%3A43890507" target="_blank" >RIV/60076658:12520/16:43890507 - isvavai.cz</a>
Result on the web
<a href="http://rsos.royalsocietypublishing.org/content/3/3/150655" target="_blank" >http://rsos.royalsocietypublishing.org/content/3/3/150655</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1098/rsos.150655" target="_blank" >10.1098/rsos.150655</a>
Alternative languages
Result language
angličtina
Original language name
Segregated water observed in a putative fish embryo cryopreservative
Original language description
Development of new cryopreservation strategies has major potential in medicine and agriculture and is critical to the conservation of endangered species that currently cannot be preserved. A critical property of any potential cryopreservative solution is its ability to prevent cell-damaging ice formation during cooling and subsequent heating. This study focuses on the freezing behaviour of promising model cryoprotective solutions. We perform neutron scattering analysis, combined with computer modelling, of the water structure after quench cooling these solutions. It is found that water in this solution forms nano-clusters encapsulated by the surrounding matrix of cryoprotectant solute molecules. We posit that these small volumes inhibit ice formation, because water does not have space for the structural relaxation required to crystallize on the timescale of the cooling process.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Royal Society Open Science
ISSN
2054-5703
e-ISSN
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Volume of the periodical
3
Issue of the periodical within the volume
3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
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UT code for WoS article
000377969200016
EID of the result in the Scopus database
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