Impact of absolute food deprivation on the reproductive system in male goldfish exposed to sex steroids

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F24%3A43909061" target="_blank" >RIV/60076658:12520/24:43909061 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1007/s00360-024-01570-4" target="_blank" >https://doi.org/10.1007/s00360-024-01570-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00360-024-01570-4" target="_blank" >10.1007/s00360-024-01570-4</a>

Result language

angličtina

Original language name

Impact of absolute food deprivation on the reproductive system in male goldfish exposed to sex steroids

Original language description

There is a link between metabolism and reproduction as metabolic hormones affect hypothalamus-pituitary-testis (HPT) hormonal functions and vice versa. The aim of the present study was to investigate the effects of negative energy balance on the reproductive system in male goldfish exposed to testosterone (T) and 17 beta-estradiol (E-2). Following 7 days of food deprivation (FD), ANOVA models showed significant FD x sex steroid interactions on sperm quality and circulating sex steroid levels. When FD effects were investigated, 11-ketotestosterone (11-KT) level and sperm motility and velocity decreased in food-deprived goldfish in the control group. In E-2-exposed goldfish, FD decreased sperm production in addition to sperm motility and velocity that coincided with an elevation of circulating E-2 level. However, FD did not significantly impact sex steroids and sperm quality in T-exposed goldfish. ANOVA models showed non-significant FD x sex steroid interactions for HSI, GSI, circulating luteinizing hormone (Lh) level, and metabolic (preproghrelin, goat and nucb2) and reproductive (kiss1, gpr54 and gnrh3) mRNAs. Furthermore, results showed that FD decreased HSI, and increased Lh levels and testicular preproghrelin and goat mRNAs, while sex steroids increased mid-brain nucb2, kiss1 and gpr54 mRNAs. Together, our results suggest that FD-induced inhibition of androgenesis resulted in diminished sperm quality associated with activation of the testicular ghrelinergic system, and negative feedback of 11-KT increased Lh level. The FD-induced testicular metabolic and hormonal system was impacted in goldfish exposed to sex steroids. However, the negative effects of FD on sperm quality were accelerated in E-2-exposed goldfish due to estrogenic activity. This study provides novel information to better understand metabolic-associated reproductive disorders in fish.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

40103 - Fishery

Project

<a href="/en/project/QK21010141" target="_blank" >QK21010141: Management of gametes and reproduction in the protection of genetic resources and the breeding program of common carp in the conditions of aquaculture in the Czech Republic</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Comparative Physiology B - Biochemical Systemic and Environmental Physiology

ISSN

0174-1578

e-ISSN

1432-136X

Volume of the periodical

194

Issue of the periodical within the volume

4

Country of publishing house

DE - GERMANY

Number of pages

16

Pages from-to

411-426

UT code for WoS article

001248445400001

EID of the result in the Scopus database

2-s2.0-85196034833