DEAD-box RNA helicase is dispensable for mitochondrial translation in Trypanosoma brucei

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F11%3A00359433" target="_blank" >RIV/60077344:_____/11:00359433 - isvavai.cz</a>

Alternative codes found

RIV/60076658:12310/11:43881335

Result on the web

<a href="http://dx.doi.org/10.1016/j.exppara.2010.06.036" target="_blank" >http://dx.doi.org/10.1016/j.exppara.2010.06.036</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.exppara.2010.06.036" target="_blank" >10.1016/j.exppara.2010.06.036</a>

Result language

angličtina

Original language name

DEAD-box RNA helicase is dispensable for mitochondrial translation in Trypanosoma brucei

Original language description

DEAD-box RNA helicase, a putative subunit of the mitochondrial ribosome of Trypanosoma brucei, has been down-regulated in the procyclic and bloodstream stage by RNA interference. Although ablation of the transcript leads to a week growth phenotype in theprocyclic cells, the protein does not seem to be essential for mitochondrial translation under standard cultivation conditions, as shown by an assay that allows visualization of the de novo synthesized proteins. Furthermore, we show that synthesis of cytochrome c oxidase subunit I and cytochrome b does not occur in the mitochondrion of the bloodstream stage.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Experimental Parasitology

ISSN

0014-4894

e-ISSN

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Volume of the periodical

127

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

4

Pages from-to

300-303

UT code for WoS article

000286486800046

EID of the result in the Scopus database

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