Conversion of the chill susceptible fruit fly larva (Drosophila melanogaster) to a freeze tolerant organism
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F12%3A00375752" target="_blank" >RIV/60077344:_____/12:00375752 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12310/12:43883594
Result on the web
<a href="http://www.pnas.org/content/early/2012/02/06/1119986109.full.pdf+html" target="_blank" >http://www.pnas.org/content/early/2012/02/06/1119986109.full.pdf+html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1073/pnas.1119986109" target="_blank" >10.1073/pnas.1119986109</a>
Alternative languages
Result language
angličtina
Original language name
Conversion of the chill susceptible fruit fly larva (Drosophila melanogaster) to a freeze tolerant organism
Original language description
This paper shows that mechanisms of freeze-tolerance studied by us previously in subarctic fly Chymomyza costata can be applied to a fruit fly of tropical origin with a weak innate capacity to tolerate even mild chilling. We found that surprisingly simple laboratory manipulations can change the chill susceptible insect to the freeze-tolerant one. Larvae of Drosophila melanogaster can then survive at subzero temperatures when approximately 50% of their body water turns to ice crystals. To achieve this goal, synergy of two fundamental prerequisites is required: (a) shutdown of larval development, including all the chill sensitive processes linked to it, by exposing larvae to low but above-lethal temperatures (quiescence), and (b) incorporating the free amino acid proline in tissues by feeding larvae a proline-augmented diet (cryopreservation).
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Proceedings of the National Academy of Sciences of the United States of America
ISSN
0027-8424
e-ISSN
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Volume of the periodical
109
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
3270-3274
UT code for WoS article
000300828200023
EID of the result in the Scopus database
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