Efficient disruption of endogenous Bombyx gene by TAL effector nucleases

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F13%3A00390514" target="_blank" >RIV/60077344:_____/13:00390514 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12310/13:43885132
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0965174812001622#" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0965174812001622#</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ibmb.2012.10.011" target="_blank" >10.1016/j.ibmb.2012.10.011</a>

Result language
angličtina
Original language name
Efficient disruption of endogenous Bombyx gene by TAL effector nucleases
Original language description
TALENS are engineered nucleases used for targeted gene disruptions in various organisms. We examined the potential of using full length TALENs for site-specific mutagenesis in silkworm. Three full-length TALEN pairs were synthesized by Golden gate assembly, used for activity examination in heterologous yeast system and finally for mutagenesis in Bombyx mori germline. All TALENs were able to generate somatic and germline mutations in silkworms albeit at low frequency.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)