African trypanosome strategies for conquering new hosts and territories: the end of monophyly?

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F22%3A00562196" target="_blank" >RIV/60077344:_____/22:00562196 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12310/22:43904679 RIV/00216208:11310/22:10448842
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S1471492222001143?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1471492222001143?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.pt.2022.05.011" target="_blank" >10.1016/j.pt.2022.05.011</a>

Result language
angličtina
Original language name
African trypanosome strategies for conquering new hosts and territories: the end of monophyly?
Original language description
Trypanosoma brucei parasites are the causative agents of African trypanosomiasis in humans, as well as surra, nagana, and dourine in animals. According to current widely used nomenclature, T. brucei is a group of five (sub) species, each causing a distinct disease and possessing unique genetic marker(s) or a combination thereof. However, minimal nuclear genome differences, sometimes accompanied by ongoing genetic exchange, robustly support polyphyly resulting from multiple independent origins of the (sub)species in nature. The ease of generating such (sub)species in the laboratory, as well as the case of overlapping hosts and disease symptoms, is incompatible with the current (sub)species paradigm, which implies a monophyletic origin. Here, we critically re-evaluate this concept, considering recent genome sequencing and experimental studies. We argue that ecotype should be used going forward as a significantly more accurate and appropriate designation.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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